After moving west and joining the famed Los Angeles Groundlings comedy improvisational troupe, Kathy Griffin began building her resume with guest starring roles on such series as "ER," and also appeared as the recurring character Sally Weaver on "Seinfeld." After her various TV guest spots, Kathy began gaining notice as a stand-up comedian and landed her own HBO Half-Hour Comedy Special. In 1998, HBO gave Griffin her own one-hour special, "A Hot Cup of Talk."

Griffin has supplied voices for characters on the animated series "Dilbert" and "The Simpsons," and she appeared in a dual role on the "X-Files" as well as in Eminem's video, "The Real Slim Shady", co-directed by Dr. Dre. Kathy co-hosted The Billboard Music Awards three years in a row, appeared on numerous talk shows including "Late Night with David Letterman," "The Tonight Show with Jay Leno," "Howard Stern" and "The View" and has been featured in the films "It's Pat" and "Four Rooms," among others.

Kathy has a great passion for reality TV. She participated in and won "Celebrity Mole" on ABC, hosted the NBC reality series "Average Joe" and hosted the MTV series "Kathy's So-Called Reality." Kathy released her hilarious comedy stand-up on DVD, "Allegedly," which is in stores now. In August 2005 Kathy's reality show, "Kathy Griffin: My Life On The D-List," debuted on Bravo as well as her stand-up special "Kathy Griffin...Is Not Nicole Kidman." The second season of her hit reality show premieres Tuesday June 6 on Bravo.